Bone scintigraphy in primary tumors of the head and neck

Bones of the face and skull may be involved directly by adjacent primary tumors of the head and neck. Radiography, at present the standard method for detection of bone involvement in such tumors, is not sufficiently sensitive. Of 22 patients who showed bone involvement in scintigraphy, radiography in 15 was initially normal, in 6 the extent of the lesion was not completely shown and only in 3 was it as informative as scintigraphy. Bone scintigraphy should become a standard method for evaluation of the context of bone invasion by tumors of the head and neck.