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Influence of age on motor nerve conduction
Indian Journal of Physiology and Pharmacology
|October 1, 1983
Summary
Motor nerve conduction velocity (MNCV) declines with age, particularly in older individuals. This study found MNCV is lower in distal nerve segments compared to proximal ones, especially in the median nerve.
Area of Science:
- Neuroscience
- Physiology
Background:
- Motor nerve conduction velocity (MNCV) is a key electrophysiological measure.
- Age-related changes in nerve function are not fully understood.
Purpose of the Study:
- To investigate the effect of age on MNCV in healthy males.
- To compare MNCV in proximal versus distal segments of the ulnar and median nerves.
Main Methods:
- Electrophysiological assessment of MNCV.
- Inclusion of 75 healthy male subjects across different age groups.
- Analysis of right ulnar and median nerves.
Main Results:
- MNCV showed a significant decrease in older age groups.
- MNCV was consistently lower in distal nerve segments compared to proximal segments.
- This distal-proximal difference was particularly significant in the median nerve.
Conclusions:
- Aging is associated with reduced motor nerve conduction velocity.
- Nerve conduction velocity is segment-dependent, with distal segments exhibiting lower values.
- These findings highlight age-related and segment-specific alterations in peripheral nerve function.