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Related Experiment Videos

Two-dimensional contrast echocardiography. II. Transpulmonary studies.

F J Ten Cate, S Feinstein, W Zwehl

    Journal of the American College of Cardiology
    |January 1, 1984
    PubMed
    Summary

    This study demonstrates a novel contrast echocardiography method for visualizing the left ventricle in dogs. The technique successfully opacified the left ventricular chamber, offering potential for enhanced cardiac imaging.

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    Area of Science:

    • Cardiovascular Imaging
    • Echocardiography
    • Medical Devices

    Background:

    • Contrast echocardiography is a valuable tool for cardiac imaging.
    • Accurate visualization of the left ventricle is crucial for diagnosing cardiac conditions.
    • Existing methods may have limitations in opacifying the left ventricular chamber and myocardium.

    Purpose of the Study:

    • To describe and evaluate a new method using contrast two-dimensional echocardiography.
    • To assess the feasibility of achieving left ventricular chamber and myocardial opacification.
    • To investigate the influence of catheter characteristics and injection parameters on opacification.

    Main Methods:

    • A novel contrast echocardiography technique was developed and tested in 152 canine studies.

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  • Utilized pulmonary capillary wedge position for contrast injection.
  • Varied catheter tip size, catheter position, injection pressure, and contrast agent type (hand-agitated vs. sonicated).

    • Main Results:

    • Left ventricular chamber opacification was consistently achieved in all studies.
    • Qualitative assessment of opacification (0-3+) showed agreement in 71% of studies.
    • Sonicated sorbitol 70% demonstrated faster opacification in the left atrium compared to Renografin-76 (2.8s vs. 6.2s).
    • Peak videointensity showed lower error with sonicated sorbitol 70% (1.4%) compared to Renografin-76 (10.4%).

    Conclusions:

    • The described method enables reliable left ventricular chamber opacification using contrast echocardiography.
    • Sonicated sorbitol 70% appears superior to sonicated Renografin-76 for this application.
    • Further research is needed to optimize myocardial opacification and clinical applicability.