Phase II enzyme induction reduces body burden of heptachlor in rats
Toxicology Letters
|January 1, 1984
Abstract:
Contrary to expectations hexadecane had no significant effect on the body clearance of heptachlor in rats. However, phase II enzyme induction altered the kinetics of heptachlor dramatically, reducing its half-life by about 3-fold. The reduction of half-life was reflected in correspondingly lowered adipose tissue and blood levels.
