Related Experiment Videos
Survival of Kn(a+) McC(a+) red cells in a patient with anti- "Kna/McCa"
The in vivo survival of Kn(a+)McC(a+) red cells in a patient with anti- "Kna/McCa" was studied using 51Cr-labeled incompatible cells. The antibody was IgG4, demonstrable at 37 degrees C in the antiglobulin test, and did not bind complement. Survival of tagged cells was 82.2 percent after 24 hours. The patient was transfused with a total of 29 units of incompatible blood with no evidence of ill effects. The direct antiglobulin test became positive after transfusion and remained positive for 2 1/2 months of observation. The findings suggest that individuals with anti- "Kna/McCa" may be transfused with Kn(a+)McC(a+) red cells.
The in vivo survival of Kn(a+)McC(a+) red cells in a patient with anti- "Kna/McCa" was studied using 51Cr-labeled incompatible cells. The antibody was IgG4, demonstrable at 37 degrees C in the antiglobulin test, and did not bind complement. Survival of tagged cells was 82.2 percent after 24 hours. The patient was transfused with a total of 29 units of incompatible blood with no evidence of ill effects. The direct antiglobulin test became positive after transfusion and remained positive for 2 1/2 months of observation. The findings suggest that individuals with anti- "Kna/McCa" may be transfused with Kn(a+)McC(a+) red cells.