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Related Experiment Videos

Retroperitoneal fibrosis. A follow-up study.

E Hem, W Mathisen

    European Urology
    |January 1, 1984
    PubMed
    Summary
    This summary is machine-generated.

    Retroperitoneal fibrosis (RPF) can be idiopathic or secondary to other conditions. Ureterolysis is an effective treatment for RPF, with most ureters functioning post-surgery, though some patients require reoperation.

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    Area of Science:

    • Nephrology
    • Urology
    • Pathology

    Background:

    • Retroperitoneal fibrosis (RPF) is a rare condition characterized by inflammation and fibrosis in the retroperitoneum.
    • RPF can lead to ureteral obstruction, kidney damage, and potentially renal failure.
    • Causes include idiopathic RPF, temporal arteritis, aortic aneurysm, and ergotamine ingestion.

    Purpose of the Study:

    • To review the etiology, pathogenesis, and treatment of retroperitoneal fibrosis.
    • To evaluate the outcomes of ureterolysis in patients with RPF.
    • To provide recommendations for managing RPF complications.

    Main Methods:

    • Retrospective review of 13 patients diagnosed with retroperitoneal fibrosis.
    • Analysis of surgical interventions, specifically ureterolysis, and their outcomes.

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  • Assessment of long-term renal function and ureteral patency.

    • Main Results:

    • 10 patients had idiopathic RPF; 3 had secondary RPF.
    • Ureterolysis was performed on 24 ureters, with 23 functioning initially.
    • Long-term follow-up (4 months to 20 years) showed 19 kidneys with free outflow; 2 were removed, and 1 remained non-functional.

    Conclusions:

    • Ureterolysis is a successful intervention for managing ureteral obstruction in retroperitoneal fibrosis.
    • Early intervention with percutaneous nephrostomy is recommended for patients with severe renal impairment, pyonephrosis, or urosepsis.
    • Understanding the diverse etiologies of RPF is crucial for effective patient management.