Meiotic studies in two infertile males with autosomal translocations

Meiotic studies were performed in two infertile male carriers of balanced reciprocal translocations between chromosomes 3;5 and 6;10. The first patient had severe oligozoospermia with all stages of meiosis present. The other patient was azoospermic with meiotic breakdown after the first meiotic division. A ring quadrivalent configuration was found in diakinesis in both cases.