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Radiation therapy for early glottic carcinomas.

P G Giri, E K Reddy, C M Mansfield

    Southern Medical Journal
    |February 1, 1984
    PubMed
    Summary
    This summary is machine-generated.

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    Primary radiation therapy is highly effective for early glottic cancers (T1N0M0), achieving a 96.7% overall control rate. Surgery is recommended only for cases where radiotherapy is unsuccessful.

    Area of Science:

    • Oncology
    • Radiation Oncology
    • Head and Neck Cancer

    Background:

    • Early glottic cancer (T1N0M0) requires effective treatment strategies.
    • Radiation therapy is a common modality for head and neck malignancies.

    Purpose of the Study:

    • To evaluate the efficacy of radiation therapy for early glottic cancers.
    • To determine the overall survival and disease control rates.

    Main Methods:

    • Retrospective analysis of 30 patients with T1N0M0 glottic cancer.
    • Treatment administered between 1973 and 1978 at the University of Kansas Medical Center.
    • Minimum follow-up of three years.

    Main Results:

    • An overall disease control rate of 96.7% (29/30 patients) was achieved.

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  • 86.7% (26/30) of patients were alive with no evidence of disease.
  • Radiotherapy failure occurred in 10% (3/30), with two patients salvaged by surgery.

    • Conclusions:

    • Primary radiation therapy is a recommended treatment for early glottic cancer.
    • Surgery serves as an effective salvage option for radiotherapy failures.
    • High rates of disease control and survival support radiotherapy as a primary modality.