[Formation of multiple round foci in the lung during amiodarone therapy]

During treatment with the antiarrhythmic agent amiodarone pulmonary infiltrates may be observed occasionally. Such a side-effect was seen in a 67-year-old patient after several months of amiodarone therapy (200 mg/d during 5 days of the week). After withdrawal of the drug the infiltrates regressed over a period of two months. No other causes for the pulmonary opacities could be established. So far, 13 patients with pulmonary changes during amiodarone treatment have been reported in the literature.