Routine studies of swallowed radionuclide transit in paediatrics: experience with 400 patients

Area of Science:

• Pediatric Gastroenterology
• Nuclear Medicine
• Diagnostic Imaging

Background:

• Evaluating foregut function in pediatric patients is crucial for diagnosing various gastrointestinal and respiratory conditions.
• Traditional methods may be invasive or less sensitive in detecting subtle abnormalities.

Purpose of the Study:

• To assess the efficacy of scintigraphy with 99m Tc-sulphur colloid for evaluating pediatric foregut function.
• To measure oesophageal transit time and gastric emptying in children.
• To determine the utility of this technique in detecting gastro-oesophageal reflux and aspiration.

Main Methods:

• Scintigraphic studies were performed on 400 pediatric patients of all ages.
• Patients swallowed 99m Tc-sulphur colloid mixed with a small volume of liquid.
• Standard gamma camera with computing facilities was used for data acquisition and analysis.
• Oesophageal transit time and gastric emptying proportions were measured.

Main Results:

• The scintigraphic procedure allowed clear visualization of foregut function.
• It proved highly effective in detecting gastro-oesophageal reflux and aspiration, particularly in neonates.
• The method is non-invasive, physiological, and suitable for routine outpatient use.

Conclusions:

• Scintigraphy with 99m Tc-sulphur colloid is a valuable tool for assessing pediatric foregut motility and diagnosing gastro-oesophageal reflux.
• Its effectiveness extends to detecting aspiration and has implications for managing conditions like oesophagitis and recurrent respiratory issues.
• This non-invasive technique offers a reliable alternative for investigating foregut dysfunction in children.