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Updated: Aug 8, 2026

Testing the Efficacy of Pharmacological Agents in a Pericardial Target Delivery Model in the Swine
Published on: July 7, 2016
Abstract:
Today's pacing techniques and technologies have gone a long way toward the ideal and in the 1980s will make further strides toward a possible universally responsive, sophisticated, single instrument. These advances include the use of programmability of at least mode, rate, output, sensitivity, and refractory period; dual-chamber as well as single-chamber pacing; CMOS and LSI circuits; lithium batteries and possibly a limited revival of plutonium batteries; new lighter, longer-lasting, positive attachment leads; and new methods of triggering pacing. However, the increase in complexity and expense of the new devices has led to a question of their need, to a disputed question as to the possibility of overuse of pacing in general, and a need to reconcile government-mandated cost containment with medical as well as socioeconomic reality.
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