[Membranoproliferative glomerulonephritis as an unusual initial manifestation in a case of plasmacytoma]

The Authors describe a case of membranoproliferative glomerulonephritis associated with nephrotic syndrome in a 50-year-old man with plasmocytoma. The bone marrow and the immunoelectrophoresis of the serum and urine showed a Bence-Jones positive multiple myeloma with plasma cells secreting only k light chain. The patient responded immediately to monthly courses of cyclophosphamide, melphalan, vincristine and prednisone. He showed still, 27 months after the diagnosis, complete remission of the disease.