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Determination of salicylic acid and aspirin in multicomponent tablets by liquid chromatography on a nonionic resin
Journal of Pharmaceutical Sciences
|August 1, 1978
Abstract:
Aspirin and free salicylic acid were determined in combinations containing caffeine, phenacetin, salicylamide, and acetaminophen by liquid chromatography on poly(methyl methacrylate) resin. Precision and accuracy were +/- 2% for salicylic acid, the latter at levels corresponding to 0.02% of the aspirin content.