Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Ultraviolet light and epidermal immunologic phenomena].

G Stingl

    Der Hautarzt; Zeitschrift Fur Dermatologie, Venerologie, Und Verwandte Gebiete
    |March 1, 1984
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Pioneers in Dermatology and Venereology: an interview with Professor Georg Stingl.

    Journal of the European Academy of Dermatology and Venereology : JEADV·2022
    Same author

    Single-cell RNA sequencing profiling in a patient with discordant primary cutaneous B-cell and T-cell lymphoma reveals micromilieu-driven immune skewing.

    The British journal of dermatology·2021
    Same author

    Analysis of anti-tumour necrosis factor-induced skin lesions reveals strong T helper 1 activation with some distinct immunological characteristics.

    The British journal of dermatology·2017
    Same author

    IgE autoreactivity in bullous pemphigoid: eosinophils and mast cells as major targets of pathogenic immune reactants.

    The British journal of dermatology·2017
    Same author

    Molecular classification of tumour cells in a patient with intravascular large B-cell lymphoma.

    The British journal of dermatology·2017
    Same author

    Pru p 3, a marker allergen for lipid transfer protein sensitization also in Central Europe.

    Allergy·2017
    Same journal

    Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete·2022
    Same journal

    [Viral infections of the skin].

    Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete·2022
    Same journal

    [Viral exanthems in children].

    Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete·2022
    Same journal

    [Erratum to: Digital health applications and data protection].

    Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete·2022
    Same journal

    [Virus-induced exanthems in returning travellers].

    Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete·2022
    Same journal

    [Venous ulcus cruris-Surgical treatment].

    Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete·2022
    See all related articles

    Ultraviolet (UV) irradiation induces antigen-specific immune suppression, likely originating from signals within the skin. Further analysis of UV-induced immunosuppression mechanisms is crucial for understanding photocarcinogenesis and preventive medicine.

    Area of Science:

    • Immunology
    • Dermatology
    • Photobiology

    Background:

    • Ultraviolet (UV) irradiation is known to alter immunological reactivity.
    • UV exposure can induce a state of antigen-specific immune suppression in experimental animals.
    • The precise mechanisms underlying UV-induced immune suppression remain unclear.

    Purpose of the Study:

    • To investigate the origin of UV-induced immune suppression, hypothesizing it stems from the skin.
    • To explore the role of skin-resident immunoactive cells in UV-induced immunosuppression.
    • To elucidate the molecular events involved in UV-induced immunosuppression.

    Main Methods:

    • Analysis of molecular events in UV-irradiated skin.
    • Assessment of immunoactive cells within the skin.

    Related Experiment Videos

  • Investigation of T-cell-dependent immune responses following UV exposure.

    • Main Results:

    • UV irradiation impairs the functional capacity of skin-resident immunoactive cells.
    • Evidence suggests that signals initiating UV-induced immune suppression originate in the skin.
    • Molecular pathways of UV-induced immunosuppression are being detailed.

    Conclusions:

    • The skin is a primary site for initiating UV-induced immune suppression.
    • Understanding these mechanisms is vital for photocarcinogenesis research.
    • Findings have implications for environmental and preventive medicine.