[Synthesis of 2-substituted alkanolphosphoric acid esters with lytic effects]

Lysolipid analogues were synthetized and tested for haemolytic activity. Initial substances were long-chain 2-methylalkanols, as well as 2-hexadecylpropane-1,3-diol. The latter compound was prepared starting with hexadecylmalonic acid diester. Among the compounds synthetized, there were also 1-acetoxy-2-hexadecylpropan-3-ol-phosphocholine and acidic-reacting lysolipid analogues.