[Biochemical and ultrastructural changes of the liver during the loss of cerebral function]

Biochemical and electron optical changes in the liver cell were recorded at the experimental brain death in dogs. The investigation results refer to a hypoxic lesion at the beginning of the brain death despite of a strong flow in the hepatic artery and the portal vein. An enlarged shunt flow is discussed to be the cause.--A distinct recovery tendency shows the morphological picture at the state of the brain death despite reducing the hepatic blood-flow and without aimed therapeutic measures. This recovery tendency appears better in the electron microscopical finding than in the behaviour of the cell metabolites.