Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Exercise-induced asthma. Physiologic and clinical considerations.

E R Bleecker

    Clinics in Chest Medicine
    |March 1, 1984
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Complex association patterns for inflammatory mediators in induced sputum from subjects with asthma.

    Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology·2018
    Same author

    Responsiveness to oral prednisolone in severe asthma is related to the degree of eosinophilic airway inflammation.

    Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology·2017
    Same author

    eQTL of bronchial epithelial cells and bronchial alveolar lavage deciphers GWAS-identified asthma genes.

    Allergy·2015
    Same author

    An airway epithelial iNOS-DUOX2-thyroid peroxidase metabolome drives Th1/Th2 nitrative stress in human severe asthma.

    Mucosal immunology·2014
    Same author

    Severe chronic allergic (and related) diseases: a uniform approach--a MeDALL--GA2LEN--ARIA position paper.

    International archives of allergy and immunology·2012
    Same author

    Predicting worsening asthma control following the common cold.

    The European respiratory journal·2008

    Exercise-induced asthma is triggered by respiratory heat and water exchange changes, reproducible by breathing cold, dry air. This condition is linked to airway hyperreactivity and bronchospasm.

    Area of Science:

    • Pulmonary Medicine
    • Exercise Physiology
    • Allergy and Immunology

    Background:

    • Exercise-induced asthma (EIA) is a common condition affecting athletes and the general population.
    • The precise mechanisms initiating EIA remain a subject of ongoing research.
    • Non-specific airways hyperreactivity is frequently observed in individuals with EIA.

    Purpose of the Study:

    • To elucidate the physiologic and clinical aspects of exercise-induced asthma.
    • To explore the role of heat and water exchange in the respiratory tract in EIA.
    • To review proposed mechanisms and therapeutic strategies for EIA.

    Main Methods:

    • Discussion of existing literature on the pathophysiology of EIA.
    • Analysis of studies involving isocapneic hyperventilation with cold, dry air.

    Related Experiment Videos

  • Review of research correlating pulmonary responses with airway hyperreactivity.

    • Main Results:

    • Alterations in respiratory heat and water exchange are implicated in triggering EIA.
    • Isocapneic hyperventilation with cold, dry air can reliably reproduce EIA symptoms.
    • Pulmonary responses during hyperventilation correlate with the degree of non-specific airways hyperreactivity.

    Conclusions:

    • Airways cooling and drying are significant factors in the development of bronchospasm.
    • Understanding these mechanisms is crucial for developing effective therapeutic approaches.
    • Further research into EIA pathophysiology can guide clinical management and treatment.