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Right ventricular performance in chronic air flow obstruction.

O Burghuber, H Bergmann, K Silberbauer

    Respiration; International Review of Thoracic Diseases
    |January 1, 1984
    PubMed
    Summary
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    Radionuclide angiocardiography using krypton-81m revealed lower right ventricular ejection fraction (RVEF) in chronic obstructive pulmonary disease patients. This method non-invasively assesses right heart afterload and pulmonary artery pressure (PAP).

    Area of Science:

    • Cardiology
    • Pulmonology
    • Nuclear Medicine

    Background:

    • Chronic obstructive pulmonary disease (COPD) can affect right heart function.
    • Assessing right ventricular pump performance and pulmonary artery pressure (PAP) is crucial in COPD management.

    Purpose of the Study:

    • To evaluate right ventricular pump performance in COPD patients using radionuclide angiocardiography.
    • To investigate the relationship between right ventricular ejection fraction (RVEF) and pulmonary artery pressure (PAP) in COPD.

    Main Methods:

    • Radionuclide angiocardiography with krypton-81m was performed on 14 COPD patients.
    • Right ventricular ejection fraction (RVEF) was measured and compared to normal volunteers.
    • Correlation between RVEF and mean pulmonary artery pressure (PAP) was analyzed.

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    Main Results:

    • COPD patients exhibited significantly lower RVEF compared to healthy controls.
    • A significant difference in RVEF was observed between patients with normal and elevated PAP.
    • A negative linear correlation was found between RVEF and mean PAP.

    Conclusions:

    • Radionuclide angiocardiography with krypton-81m provides a non-invasive method for assessing right heart afterload.
    • This technique indirectly estimates pulmonary artery pressure (PAP) in COPD patients.
    • RVEF serves as an indicator of elevated PAP in the context of COPD.