[Chromosomal polymorphism in patients with ovarian hypofunction of central origin]

Comparative data are reported on chromosome polymorphism in adolescent patients with ovarian hypofunction of central origin and healthy women. Chromosome variants with small and very small heterochromatin blocks were found to prevail in the adolescent patients. The incidence of pericentric inversions in chromosomes 1 and 9 was found to be significantly increased in the girls with ovarian hypofunction.