Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Methods for obtaining fetal blood and its characterization]

V A Bakharev, N A Karetnikova, IantovskiO

    Akusherstvo I Ginekologiia
    |January 1, 1994
    PubMed
    Summary

    Fetal blood collection via cordocentesis and cardiocentesis is feasible for prenatal diagnostics. Success depends on careful obstetrical assessment, equipment, and physician expertise.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    High frequency of a splice mutation in intron 2 of the 21-hydroxylase gene in Russia could be partly explained by a founder effect.

    Human mutation·1998
    Same author

    Preliminary investigation of mutations in 21-hydroxylase gene in patients with congenital adrenal hyperplasia in Russia.

    Human mutation·1995
    Same author

    [Diagnosis of heterozygote carrier of mutant gene of 21-hydroxylase].

    Akusherstvo i ginekologiia·1995
    Same author

    [The steroid content of the amniotic fluid in the 1st and 2nd pregnancy trimesters in 21-hydroxylase insufficiency and in fetal central nervous system defects].

    Akusherstvo i ginekologiia·1995
    Same author

    [Congenital dysfunction of adrenal cortex - detection of new mutant gene of 21-hydroxylase].

    Vestnik Rossiiskoi akademii meditsinskikh nauk·1994
    Same author

    [Antenatal diagnosis of the fetus].

    Akusherstvo i ginekologiia·1994

    Area of Science:

    • Obstetrics and Gynecology
    • Fetal Medicine
    • Prenatal Diagnostics

    Background:

    • Fetal blood sampling is crucial for prenatal diagnosis.
    • Techniques like cordocentesis and cardiocentesis offer direct fetal access.
    • Optimizing these procedures is essential for reliable results.

    Purpose of the Study:

    • To evaluate the feasibility and success factors of fetal blood collection.
    • To analyze the utility of cordocentesis and cardiocentesis in prenatal care.
    • To identify key elements influencing positive outcomes in fetal blood sampling.

    Main Methods:

    • Collected fetal blood from 83 women using cardocentesis (31 cases) and cordocentesis (52 cases).
    • Analyzed obstetrical situations and recorded fetal heartbeats during procedures.
    • Performed blood group, rhesus, Kleihauer-Betke test, karyotype, HLA phenotype, and DNA analysis on collected samples.

    Main Results:

    • Successful fetal blood collection was achieved in the majority of cases.
    • Positive outcomes were correlated with accurate obstetrical assessment, high-resolution equipment, and experienced physicians.
    • Various fetal analyses, including blood typing and genetic testing, were successfully performed.

    Conclusions:

    • Cordocentesis and cardocentesis are viable methods for obtaining fetal blood for diagnostic purposes.
    • The success rate is significantly influenced by the skill of the medical team and the quality of equipment.
    • Careful consideration of these factors is necessary for the practical application of fetal blood sampling techniques.

    Related Experiment Videos