Effect of 30% sodium sulfacetamide on corneal sensitivity

This study compares the effect of 10 and 30% sodium sulfacetamide on corneal sensitivity. The corneal sensitivity was measured on 11 subjects with a Cochet -Bonnet aesthesiometer without any drug, 10 and 30% sodium sulfacetamide . The results obtained for the mean corneal sensitivities (mean +/- standard error) for the control, 10 and 30% sodium sulfacetamide were 1.07 +/- 0.025, 1.09 +/- 0.023, and 1.36 +/- 0.10 gm/mm2, respectively. We found that there was no statistical difference between the control value and 10% sodium sulfacetamide , but the 30% produced a significant decrease in corneal sensitivity when compared to the control and 10% concentration.