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Related Experiment Videos

Interference in food aversion conditioning by reducing drug dose or conditioning trials.

D P Fenner, I L Bernstein

    Behavioral and Neural Biology
    |January 1, 1984
    PubMed
    Summary

    Intense food aversions are not resistant to interference. Researchers found that a second food interfered with conditioning of aversion to a target food, especially when conditioning was weakened.

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    Area of Science:

    • Behavioral neuroscience
    • Learning and memory
    • Conditioned taste aversion

    Background:

    • Previous research indicated food aversions are resistant to interference.
    • This resistance was often attributed to the strong associative properties of food.
    • An alternative explanation is that intense conditioned aversions, in general, resist interference.

    Purpose of the Study:

    • To investigate if interference effects can be demonstrated in food aversion conditioning.
    • To examine if reducing drug dose or conditioning trials facilitates interference.
    • To test the hypothesis that interference is more likely under conditions of weaker conditioning.

    Main Methods:

    • Wistar rats were used as subjects.
    • Food aversion conditioning was manipulated by varying the dose of cyclophosphamide (20 vs 40 mg/kg).
    • The number of conditioning trials was also varied to alter conditioning strength.

    Main Results:

    • Interference with target food aversion conditioning was successfully demonstrated.
    • The presence of a second food interfered with the conditioning of aversion to the target food.
    • Interference was facilitated under conditions expected to produce slower or weaker conditioning.

    Conclusions:

    • Food aversion conditioning is susceptible to interference effects.
    • Interference is more pronounced when conditioning is weakened (e.g., lower drug dose, fewer trials).
    • These findings suggest that interference is a general property of intense conditioned aversions, not specific to food targets.

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