Laboratory preparation and evaluation of a multiparameter hemocytometry control

Area of Science:

• Clinical Laboratory Science
• Hematology
• Quality Control

Background:

• Hemocytometry is crucial for blood cell counting.
• Existing controls may lack comprehensive multiparameter analysis.
• Internal quality control is essential for laboratory performance.

Purpose of the Study:

• To develop a novel multiparameter hemocytometry control.
• To incorporate stabilized human platelets into a blood cell control.
• To evaluate the precision and stability of the new control.

Main Methods:

• A simplified and inexpensive fixation procedure for human platelets.
• Integration of platelets with existing white and red blood cell controls.
• Evaluation using the Coulter counter Model S Plus-II.

Main Results:

• The multiparameter control demonstrated good precision.
• Acceptable mechanical stability was observed for at least 7 weeks.
• The control is suitable for continuous self-auditing in laboratories.

Conclusions:

• The developed multiparameter hemocytometry control is effective.
• It enhances internal quality control by enabling continuous performance improvement.
• The protocol is practical for laboratory implementation.