Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Cognitive processes in insulin-dependent diabetes.

M Franceschi, R Cecchetto, F Minicucci

    Diabetes Care
    |May 1, 1984
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    The incidence of psychotic disorders in the Republic of Ireland: a systematic review.

    Irish journal of psychological medicine·2023
    Same author

    Use of Advanced Flexible Modeling Approaches for Survival Extrapolation from Early Follow-up Data in two Nivolumab Trials in Advanced NSCLC with Extended Follow-up.

    Medical decision making : an international journal of the Society for Medical Decision Making·2022
    Same author

    Influence of silicon morphology on direct current plasma electrolytic oxidation process in AlSi10Mg alloy produced with laser powder bed fusion.

    Scientific reports·2022
    Same author

    Use of healthcare REsources and associated COsts in controlled versus uncontrolled carcinoid SYndrome in patients with neuroendocrine tumours: the RECOSY study.

    Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico·2021
    Same author

    Real-life efficacy and safety of Ustekinumab as second- or third-line therapy in Crohn's disease: results from a large Italian cohort study.

    European review for medical and pharmacological sciences·2021
    Same author

    Correction to: Inflammatory bowel disease (IBD) position statement of the Italian Society of Colorectal Surgery (SICCR): general principles of IBD management.

    Techniques in coloproctology·2020
    Same journal

    A Secular Increase in the Incidence of Islet Autoimmunity Among Colorado Children With Moderate-Risk HLA Genotypes.

    Diabetes care·2026
    Same journal

    Clinical and Biochemical Recovery From Immune Checkpoint Inhibitor-Induced Diabetes With Seroconversion of GAD Antibodies.

    Diabetes care·2026
    Same journal

    State Insulin Out-of-Pocket Cap Policies and Estimated Eligible Populations in the United States, 2019-2026.

    Diabetes care·2026
    Same journal

    Genetic Determinants of Macronutrient Intake Are Associated With Specific Food Intake in Youth: A Cohort Study Across Childhood and Adolescence.

    Diabetes care·2026
    Same journal

    A Novel Electronic Medical Record Search Method to Identify Patients With Ketosis-Prone Diabetes: Implications for Discovery of Atypical Diabetes.

    Diabetes care·2026
    Same journal

    Real-Time Continuous Glucose Monitoring Among People With Type 2 Diabetes and End-Stage Kidney Failure Undergoing Maintenance Hemodialysis: A Randomized Clinical Trial.

    Diabetes care·2026
    See all related articles

    Patients with insulin-dependent diabetes mellitus (IDDM) showed mild cognitive deficits in memory and reasoning compared to controls. These deficits were not linked to disease duration or severity, suggesting complex underlying causes.

    Area of Science:

    • Neuroscience
    • Endocrinology
    • Psychology

    Background:

    • Insulin-dependent diabetes mellitus (IDDM) is a chronic condition affecting millions globally.
    • The impact of IDDM on cognitive function in neurologically asymptomatic individuals requires further elucidation.
    • Previous research suggests potential links between diabetes and cognitive impairment, but findings are often inconsistent.

    Purpose of the Study:

    • To investigate cognitive processes in neurologically asymptomatic patients with IDDM.
    • To compare the performance of diabetic patients with normoglycemic controls across various cognitive domains.
    • To explore potential correlations between neuropsychological deficits and disease characteristics such as duration and severity.

    Main Methods:

    • A cohort of patients with relatively severe but uncomplicated IDDM was recruited.

    Related Experiment Videos

  • A matched group of normoglycemic individuals served as controls.
  • Cognitive functions assessed included global memory, abstract reasoning, eye-hand coordination, intelligence, concentration, attention, spatial, visual, and psychomotor tests.

    • Main Results:

    • The IDDM group exhibited significantly poorer performance in global memory, abstract reasoning, and eye-hand coordination compared to controls.
    • No significant differences were observed between groups in tests of intelligence, concentration, attention, spatial, visual, or psychomotor abilities.
    • Neuropsychological deficits did not correlate with the duration or severity of diabetes.

    Conclusions:

    • Mild cognitive deficits in specific domains (memory, reasoning, coordination) are present in some IDDM patients without neurological symptoms.
    • The etiology of these deficits remains unclear, with possibilities including vascular, metabolic, or emotional factors.
    • Findings should be interpreted cautiously and may not apply to diabetic patients with superior metabolic control.