Experimental investigations on the penetration into the eyeball of iron administered intraorbitally

In order to elucidate the still controversial question whether iron foreign bodies located in the orbit can produce siderosis bulbi, the authors studied the concentration of iron in the aqueous of rabbits in which the metal was placed outside the eyeball, close to the exposed sclera. It was found that iron penetrates into the eye, its concentration in the aqueous increasing with the lapse of time. It was also found that this concentration was distinctly higher in animals which had received higher amounts of iron.