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Updated: Aug 15, 2026

A Murine Model of Myocardial Ischemia-reperfusion Injury through Ligation of the Left Anterior Descending Artery
Published on: April 10, 2014
[Spontaneous dissection of the coronary arteries]
Abstract:
We describe a 31 years old female who suffered an spontaneous dissection of the left main coronary trunk. She presented with an acute hemorrhagic myocardial infarction complicated with bifascicular block and fatal left ventricular failure. Pathological features demonstrated severe proximal left coronary artery intimal dissection and extensive hemorrhagic infarction of the left ventricle, as well as absence of atherosclerotic aortic or coronary artery disease. The severity of the clinical picture and relentless deterioration of the patient precluded the utilization of coronary arteriography to assess an emergency surgical procedure. Early and vigorous management including emergency coronary angiography, balloon counterpulsation and surgical treatment are stressed and should be carefully weighted in similar cases.
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