Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Immunological regulation of epithelial function.

G A Castro

    The American Journal of Physiology
    |November 1, 1982
    PubMed
    Summary
    This summary is machine-generated.

    Lamina propria cells in the small intestine mucosa regulate epithelial cell functions, influencing differentiation and activity. This highlights a potential adaptive immune mechanism within the gut lining.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Comedolytic effect and reduced skin irritation of a new formulation of all-trans retinoic acid-loaded solid lipid nanoparticles for topical treatment of acne.

    Archives of dermatological research·2011
    Same author

    Anti-ulcerogenic effect of a whey protein isolate and collagen hydrolysates against ethanol ulcerative lesions on oral administration to rats.

    Journal of medicinal food·2010
    Same author

    Solvent extraction of organic acids from stillage for its re-use in ethanol production process.

    Waste management & research : the journal of the International Solid Wastes and Public Cleansing Association, ISWA·2009
    Same author

    In vitro impact of a whey protein isolate (WPI) and collagen hydrolysates (CHs) on B16F10 melanoma cells proliferation.

    Journal of dermatological science·2009
    Same author

    Protective effect of collagen derivates on the ulcerative lesions caused by oral administration of ethanol.

    Journal of medicinal food·2007
    Same author

    Combined interleukin-12 and topical chemotherapy for established Leishmaniasis drastically reduces tissue parasitism and relapses in susceptible mice.

    The Journal of infectious diseases·2001
    Same journal

    Blood coagulation in fish.

    The American journal of physiology·2011
    Same journal

    Renal tubular reabsorption, metabolic utilization and isomeric fractionation of lactic acid in the dog.

    The American journal of physiology·2010
    Same journal

    The inactivation of placental toxin by human serum.

    The American journal of physiology·2010
    Same journal

    Adrenal function following ovariectomy in the rat.

    The American journal of physiology·2010
    Same journal

    Capillary permeability; perfusion of frog and guinea pig hind limbs.

    The American journal of physiology·2010
    Same journal

    Evaluation of protective measures against sunburn.

    The American journal of physiology·2010
    See all related articles

    Area of Science:

    • Gastroenterology
    • Immunology
    • Cell Biology

    Background:

    • The small intestine mucosa harbors complex interactions between epithelial and immune cells.
    • Host-parasite interactions reveal significant interplay within the intestinal mucosa.
    • Immune responses are traditionally attributed to non-epithelial cells.

    Purpose of the Study:

    • To propose a hypothesis on the regulatory role of lamina propria cells in small intestine epithelial cell function.
    • To explore the immunophysiological interplay within the intestinal mucosa.
    • To investigate how immune reactions impact epithelial cell activities.

    Main Methods:

    • Literature survey focusing on immunophysiology and host-parasite interactions in the small intestine.
    • Analysis of studies detailing immune responses in helminth infections.

    Related Experiment Videos

  • Examination of epithelial cell responses to immunological signals.

    • Main Results:

    • Immunological reactions in helminth infections affect epithelial cell differentiation, development, and functions (secretory, absorptive, digestive).
    • Epithelial cells can be bystander cells or effector components in immune-mediated inflammation.
    • Epithelial cells respond to signals from other cells, suggesting a regulatory role for lamina propria cells.

    Conclusions:

    • Lamina propria cells play a crucial regulatory role in small intestine epithelial cell functions.
    • Epithelial cells' involvement in immune responses implies a sophisticated local adaptive mechanism.
    • Further research is needed to confirm the 'memory' capabilities of epithelial cells in response to immune commands.