[Correlation of erythrocyte sodium concentration and the KG-value in variable peripheral insulin levels]

In pregnant women with physiological hyperinsulinism and in a control group with lower peripheral insulin concentrations after glucose load was investigated, whether differences in the peripheral insulin content involve different relations between the KG-value and the sodium concentration of the erythrocytes. Despite the differences in the peripheral insulin content during the intravenous glucose tolerance test negative correlations between the KG-value and the sodium concentration of the erythrocytes were found in the groups investigated. From this was concluded that these correlations are not based on changes of the peripheral insulin level, as they were established in the present examinations. A conception was presented issuing from the fact that the negative correlation between the KG-value and the sodium concentration is based on properties of the cell membrane which influence the intracellular sodium concentration as well as the effect of insulin in the cell.