Related Experiment Video
Updated: Aug 15, 2026

Real-time Imaging of Leukotriene B4 Mediated Cell Migration and BLT1 Interactions with β-arrestin
Published on: December 23, 2010
A review on the natural mediators of inflammatory leucotaxis
Abstract:
The molecular mechanisms of leucotaxis in several types of cutaneous inflammation (including active or reversed passive Arthus reaction in rabbit and rat, thermal injury in rabbit, DNP-ascaris extract-induced hypersensitivity reaction in guinea pig and PPD-induced delayed hypersensitivity reaction in guinea pig) were discussed. The chemotactic factors listed here were separated from the inflamed sites and characterized biologically or physicochemically. These agents seemed to satisfy many or some of the criteria necessary for the mediators of inflammatory leucotaxis; they included three types of neutrophil chemotactic factors, of macrophage chemotactic factors and of eosinophil chemotactic factors, or four types of lymphocyte chemotactic factors. Such heterogeneity of chemotactic factors for each leucocyte migration suggested the presence of their respective subpopulations with different biological functions; there lies a new field in the study on the functional specificity of these inflammatory chemotactic factors.
More Related Videos
12:50Screening Assays to Characterize Novel Endothelial Regulators Involved in the Inflammatory Response
Published on: September 15, 2017
10:39Advanced Imaging of Lung Homing Human Lymphocytes in an Experimental In Vivo Model of Allergic Inflammation Based on Light-sheet Microscopy
Published on: April 16, 2019
Related Concept Videos
Inflammation
Antiasthma Drugs: Leukotriene Modifiers
Leukotriene modifiers work through two distinct mechanisms:
Inflammatory Response
Inflammation can be triggered by various stimuli, such as impact, abrasion, chemical irritation, infections, and extreme hot or cold temperatures. These can damage cells and connective tissue fibers,...
Acute Inflammation I: Inflammatory Response
Acute Inflammation II: Cellular Phase
Acute Inflammation III: Local and Systemic Effects