The isocentric fast neutron therapy facility at Edinburgh

Area of Science:

• Medical Physics
• Radiation Oncology
• Nuclear Medicine

Background:

• Fast neutron therapy offers potential advantages in treating certain radioresistant tumors.
• Implementing advanced radiotherapy techniques requires careful consideration of beam delivery and radiation safety.

Purpose of the Study:

• To describe the operational features and safety aspects of a new isocentric fast neutron therapy beam.
• To assess the radiation dose to personnel during the operation of this novel radiotherapy facility.

Main Methods:

• Installation and commissioning of an isocentric fast neutron beam using a beryllium target and 15 MeV deuterons.
• Detailed characterization of the facility, including shielding design and neutron activation mitigation strategies.
• Measurement of prompt radiation leakage and induced radioactivity, alongside personnel dosimetry.

Main Results:

• The isocentric mounting allows for improved beam penetration and treatment planning flexibility.
• Measured whole-body dose-equivalent to radiographers was approximately 6 microSv per patient treated over eight months.
• Effective shielding and activation control measures were implemented and validated through measurements.

Conclusions:

• The new isocentric fast neutron therapy facility is operational and safe for clinical use.
• The facility demonstrates a low radiation dose to healthcare professionals, supporting its long-term viability.
• This advancement in radiotherapy provides a valuable tool for treating complex cancers, with potential for improved patient outcomes.