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Urinary infection in renal stone patients
European Urology
|January 1, 1980
Summary
Urinary tract infections are uncommon in kidney stone patients but more frequent in women. Urea-splitting bacteria cause many stones, with types varying by sex and drug resistance. Bacterial sensitivity to common drugs was assessed.
Area of Science:
- Urology
- Microbiology
- Infectious Diseases
Background:
- Urinary tract infections (UTIs) occur in less than 10% of renal stone formers.
- UTIs are three times more prevalent in women than men.
- Urea-splitting bacteria are implicated in a significant portion of stone formation cases.
Purpose of the Study:
- To investigate the prevalence and types of bacteria in renal stone formers.
- To analyze the variation in bacterial types based on sex and drug resistance.
- To determine the sensitivity of these bacteria to commonly used therapeutic drugs.
Main Methods:
- Bacteriological analysis of urine samples from renal stone formers.
- Categorization of bacterial species, including Proteus, Klebsiella, pyocyaneus, and staphylococcus.
- Antimicrobial susceptibility testing against eight common drugs.
Main Results:
- Urea-splitting bacteria were identified in two-thirds of the cases.
- Bacterial prevalence differed between sexes.
- Variations in bacterial resistance to therapies were observed.
Conclusions:
- While UTIs are not the primary cause of renal stones, specific bacteria play a key role.
- Understanding bacterial profiles and drug sensitivities is crucial for effective treatment of UTIs in stone formers.
- Sex and drug resistance influence the choice of antimicrobial therapy.