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[Penile leiomyosarcoma. Ultrastructural study (author's transl)].

M Armijo, E Herrera, F de Dulanto

    Annales De Dermatologie Et De Venereologie
    |March 1, 1978
    PubMed
    Summary
    This summary is machine-generated.

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    A rare penile leiomyosarcoma case in a 70-year-old farmer showed recurrence after initial excision. Subsequent wide local excision was successful, highlighting this low-grade tumor

    Area of Science:

    • Urology
    • Oncology
    • Pathology

    Background:

    • Penile leiomyosarcoma is an exceptionally rare malignancy, with only 15 prior cases documented in medical literature.
    • This report details an additional case, contributing to the limited understanding of this rare penile tumor.

    Observation:

    • A 70-year-old male farmer presented with a penile leiomyosarcoma.
    • Initial treatment involved excision/biopsy, followed by recurrence of tumors on the glans and prepuce six months later.
    • Ultrastructural analysis revealed polymorphic cells, reduced myofilaments, nuclear membrane irregularities, vascular proliferation, and interstitial hemorrhages.

    Findings:

    • The tumor was classified as a superficial leiomyosarcoma of low malignancy, consistent with McKenzie Pratt et Ross criteria.
    • Wide local excision and direct suture proved effective, with no recurrence observed in the subsequent eight months.

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  • Differential diagnosis considered epithelioid sarcoma of Enzinger.

    • Implications:

    • Simple excision, avoiding extensive mutilation, appears to be a suitable treatment for this low-grade penile malignancy.
    • This case underscores the importance of thorough histopathological and ultrastructural examination for accurate diagnosis and classification.
    • Further research and case reporting are crucial for improving the management of rare penile tumors like leiomyosarcoma.