Effects of carbaryl on variable interval response rates in rats

Sic male rats were trained on a variable interval 5 min schedule of reinforcement. Each rat, serving as its own control, was given itraperitoneal (IP) and intramuscular (IM) injections of 1, 3, 5, and 10 mg/kg l-naphthyl N-methylcarbamate (carbaryl). There were significant decreases in response rate following 3, 5, and 10 mg/kg IP injections and 5 and 10 mg/kg IM injections of carbaryl.