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Related Experiment Videos

Renal function in protein-energy malnutrition.

R Paniagua, D Santos, R Muñoz

    Pediatric Research
    |November 1, 1980
    PubMed
    Summary
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    Children with severe malnutrition, specifically marasmus and kwashiorkor, showed normal kidney function after recovery from infections and electrolyte imbalances. This suggests that impaired renal performance in malnutrition may be reversible.

    Area of Science:

    • Pediatric Nephrology
    • Nutritional Science
    • Human Physiology

    Background:

    • Advanced protein-energy malnutrition in children is often associated with impaired renal function.
    • Previous studies indicated reduced glomerular filtration rate, renal plasma flow, and urine concentrating ability.

    Purpose of the Study:

    • To investigate renal function in children with marasmus and kwashiorkor after recovery from acute illness.
    • To determine if renal performance abnormalities in malnutrition are persistent or reversible.

    Main Methods:

    • Evaluated glomerular filtration rate, renal plasma flow, and urine concentrating ability.
    • Studied eight marasmic infants and eight children with kwashiorkor.
    • Assessed renal function after resolution of infections and electrolyte disturbances.

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    Main Results:

    • Children with marasmus and kwashiorkor demonstrated practically normal renal performance.
    • Key renal functions, including filtration and concentration, appeared unimpaired post-recovery.

    Conclusions:

    • Renal function impairments observed in children with severe malnutrition may be temporary.
    • Prompt treatment and recovery from acute complications can restore normal kidney function in these patients.