[Urinary glycosaminoglycans in peptic ulcer, chronic gastritis, and normal subjects]

Excretion of glycosaminoglycans with urine in patients with duodenal ulcer was lowered due to a distinct decrease in amount of chondroitin sulphates. If the ulcer was localized in stomach and in chronic gastritis the glycosaminoglycan excretion was near the normal level. During the acute period of duodenal ulcer chondroitin sulphate deficiency was compensated by an increased production of hyaluronic acid, while at the period of clinical remission a stimulation of heparin production was noted.