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Hyperrugosity in gastric carcinoma: radiographic, endoscopic, and pathologic features
AJR. American Journal of Roentgenology
|March 1, 1981
Summary
Atypical rugal fold morphology in gastric carcinoma can mimic benign conditions, leading to misdiagnosis. Early identification through endoscopic biopsy is crucial for accurate diagnosis and treatment of diffuse infiltrating gastric cancer.
Area of Science:
- Gastroenterology
- Oncology
- Pathology
Background:
- Rugal folds in the stomach can exhibit hyperrugosity in diffuse infiltrating gastric carcinoma.
- Atypical features of these folds can lead to misdiagnosis as benign gastropathies or lymphomas.
Purpose of the Study:
- To review the morphology of rugal folds in gastric carcinoma.
- To highlight the challenges in diagnosing diffuse infiltrating lesions based on rugal fold appearance.
- To emphasize the importance of endoscopic biopsies for accurate diagnosis.
Main Methods:
- Review of morphological features of rugal folds in patients with gastric carcinoma.
- Analysis of cases with atypical rugal fold presentation.
- Correlation of endoscopic and radiographic findings with pathologic diagnosis.
Main Results:
- Six out of 27 patients with diffuse infiltrating gastric carcinoma showed atypical rugal fold enlargement, irregularity, and tortuosity.
- These atypical features, with preserved gastric volume and function, were misdiagnosed in some cases.
- Endoscopic biopsies were effective in establishing a correct diagnosis in most instances.
Conclusions:
- Hyperrugosity of gastric rugal folds can be a sign of diffuse infiltrating carcinoma.
- Radiologic and endoscopic diagnostic pitfalls exist due to atypical presentations.
- Deep endoscopic biopsies are essential for differentiating malignant from benign conditions.