Thrombotic angiokeratoma circumscriptum simulating melanoma.

Area of Science:

• Dermatology
• Pathology
• Oncology

Background:

• Angiokeratomas are benign vascular tumors.
• Differential diagnosis of skin lesions is crucial.

Observation:

• Three cases of solitary angiokeratomas are presented.
• Two were circumscribed (Fabry) type, one was Mibelli type.
• Extensive thrombosis developed in the angiokeratomas.

Findings:

• The thrombosed angiokeratomas appeared as nodular, bluish-black lesions.
• These lesions clinically simulated nodular melanoma.

Implications:

• Clinicians must consider angiokeratoma with thrombosis in the differential diagnosis of suspected melanoma.
• Accurate diagnosis prevents unnecessary aggressive treatment.