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Prinzmetal's variant angina.

E Sandøe, R Vilhelmsen, F Efsen

    Acta Medica Scandinavica. Supplementum
    |January 1, 1981
    PubMed
    Summary
    This summary is machine-generated.

    Prinzmetal

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    Area of Science:

    • Cardiology
    • Internal Medicine

    Background:

    • Prinzmetal's variant angina is characterized by coronary artery spasm.
    • Diagnosis can be challenging due to transient ischemic events and ECG abnormalities.

    Purpose of the Study:

    • To present a series of patients with Prinzmetal's variant angina.
    • To describe diagnostic challenges, clinical features, and treatment outcomes.

    Main Methods:

    • Case series of 12 consecutive patients.
    • Clinical evaluation, ECG monitoring, and coronary arteriography.
    • Assessment of treatment efficacy with nitroglycerin and calcium antagonists.

    Main Results:

    • A majority of patients were male and under 60.
    • Delayed diagnosis was common due to intermittent symptoms and ECG difficulties.

    Related Experiment Videos

  • High incidence of arrhythmias (8/12), with two requiring DC conversion.
  • Coronary arteriography showed minimal to single-vessel disease.
  • Nitroglycerin effective for acute attacks; calcium antagonists effective long-term.

    • Conclusions:

    • Prinzmetal's variant angina is rare, but coronary artery spasm is a significant factor in coronary artery disease.
    • Coronary artery spasm contributes to arrhythmias, sudden death, and myocardial infarction.