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Updated: Aug 13, 2026

Comprehensive Evaluation of the Effectiveness and Safety of Placenta-Targeted Drug Delivery Using Three Complementary Methods
Published on: September 10, 2018
[Pharmacotherapy during pregnancy. Teratological aspects (author's transl)]
Abstract:
Accidental pharmacotherapy in unrecognized pregnancy gives occasion for human genetic counseling to an increasing extent. In this, it must be clarified to what stage of development a drug was administered, whether a teratogenic effect is to be assumed, how long the effect lasts and whether compensation is possible for the damage which has occurred. Furthermore, genetic and non-genetic induced differences in the uptake, metabolization and excretion of drugs and the extent of the genetically induced sensitivity in special areas of the organ anlage in the embryo must be taken into account in the counseling.
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