[Withdrawal syndrome following beta blocker therapy (author's transl)]

An account is given of two cases of withdrawal syndrome following discontinuation of an antihypertensive treatment with a single daily dose of Teneretic mite (atenolol/chlortalidone). In one case two different beta blockers had been discontinued, however the withdrawal syndrome occurred in one instance only. One female patient presented signs of CAD, the other hypokalemia. Resumption of treatment with the same beta blocker promptly caused the symptoms to disappear. The pathogenesis of the withdrawal syndrome still being obscure, various postulates are raised in respect of beta blocker therapy.