Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Osteopenia in juvenile diabetes.

R M Shore, R W Chesney, R B Mazess

    Calcified Tissue International
    |January 1, 1981
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Malignant melanoma of the vulva: an extension of cutaneous melanoma?

    Gynecologic oncology·2011
    Same author

    Concurrent chemoradiation for locally advanced carcinoma of the cervix: where are we in 2006?

    Annals of oncology : official journal of the European Society for Medical Oncology·2006
    Same author

    Second-look operation improves survival in suboptimal, debulked, stage III ovarian cancer.

    International journal of gynecological cancer : official journal of the International Gynecological Cancer Society·2005
    Same author

    Gemcitabine reverses platinum resistance in platinum-resistant ovarian and peritoneal carcinoma.

    International journal of gynecological cancer : official journal of the International Gynecological Cancer Society·2005
    Same author

    A review of intravenous versus oral vitamin D hormone therapy in hemodialysis patients.

    Clinical nephrology·2003
    Same author

    Chemoradiotherapy for cervical cancer.

    European journal of cancer (Oxford, England : 1990)·2002
    Same journal

    Capsanthin Attenuates Osteoporosis by Targeting the Urotensin II Receptor Pathway to Inhibit Oxidative Stress and NLRP3 Inflammasome Activation.

    Calcified tissue international·2026
    Same journal

    ODAPH (p.Arg77*) Phenotype and Onset of Ameloblast Pathology During Postsecretory Transition Demonstrated by FIB-SEM Analyses of Odaph<sup>C41*/C41*</sup> Mice.

    Calcified tissue international·2026
    Same journal

    Cytokine Networks Reprogramming the Osteo-Immune Microenvironment in Cancer Bone Metastasis.

    Calcified tissue international·2026
    Same journal

    Associations between controlling nutritional status and mortality in osteoporosis: evidence from NHANES, 2005-2018.

    Calcified tissue international·2026
    Same journal

    Gut Microbiota-Derived TMAO Drives MC3T3-E1 Senescence and Osteogenic Dysfunction via cGAS-STING-NF-κB Signaling: Implications for Age-Related Bone Loss.

    Calcified tissue international·2026
    Same journal

    Artificial Intelligence Approaches for Osteoporotic Fracture Risk Prediction Using Administrative Health Data: A Systematic Review.

    Calcified tissue international·2026
    See all related articles

    Children with diabetes mellitus exhibit lower bone mineral content, regardless of disease duration. Higher insulin doses were observed in children with reduced bone density, indicating a potential link between diabetes management and bone health in pediatric patients.

    Area of Science:

    • Pediatric Endocrinology
    • Metabolic Bone Disease
    • Diabetes Mellitus Research

    Background:

    • Diabetes mellitus can affect bone metabolism.
    • Osteopenia is a concern in children with chronic diseases.
    • Understanding bone mineral status in pediatric diabetes is crucial.

    Purpose of the Study:

    • To assess bone mineral status in children with diabetes mellitus.
    • To investigate factors associated with bone demineralization in this population.
    • To evaluate the relationship between diabetes duration, insulin dosage, and bone density.

    Main Methods:

    • Single photon absorptiometry was used to measure bone mineral content.
    • Bone mineral content was compared to age, sex, height, and weight-predicted values.

    Related Experiment Videos

  • Data on diabetes duration, insulin dose, growth, renal function, and serum calcium/phosphorus were collected.

    • Main Results:

    • Children with diabetes had 13% lower mean bone mineral content than predicted.
    • Osteopenia was present even in children with diabetes duration of one year or less.
    • Demineralized children received higher daily insulin doses; no associations with sex, growth, renal function, or serum minerals were found.

    Conclusions:

    • Children with diabetes mellitus frequently present with reduced bone mineral content.
    • Early-onset diabetes does not appear to mitigate osteopenia risk.
    • Higher insulin requirements may be linked to decreased bone mineral density in pediatric diabetes.