Corneal chrysiasis and clinical improvement with chrysotherapy in rheumatoid arthritis

The deposition of gold in the cornea-ocular chrysiasis-is a normal event during chrysotherapy. It may reflect tissue deposition of gold and be of value in predicting clinical improvement or toxic reactions. We studied 21 patients with rheumatoid arthritis on chrysotherapy but could find no relationship between the appearance of ocular chrysiasis, clinical improvement, and toxicity.