Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Immunization against dental caries. A review.

A H Rogers

    Australian Dental Journal
    |April 1, 1982
    PubMed
    Summary

    Developing a safe and effective vaccine against dental caries is challenging. Research focuses on Streptococcus mutans, but challenges remain in vaccine safety, efficacy, and long-term protection.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Clonal diversity in biofilm formation by Enterococcus faecalis in response to environmental stress associated with endodontic irrigants and medicaments.

    International endodontic journal·2014
    Same author

    Influence of arginine on the coexistence ofStreptococcus mutans andS. milleri in glucose-limited mixed continuous culture.

    Microbial ecology·2013
    Same author

    Intravitreal bevacizumab (Avastin) treatment of choroidal neovascularisation in patients with angioid streaks.

    The British journal of ophthalmology·2008
    Same author

    The behaviour of Fusobacterium nucleatum chemostat-grown in glucose- and amino acid-based chemically defined media.

    Anaerobe·2006
    Same author

    Why be down in the mouth? Three decades of research in oral microbiology.

    Australian dental journal·2005
    Same author

    Microbiological evaluation of endodontic files after cleaning and steam sterilization procedures.

    Australian dental journal·2004

    Area of Science:

    • Immunology
    • Microbiology
    • Vaccinology

    Background:

    • Dental caries is a significant global health issue.
    • Streptococcus mutans is widely considered the primary etiological agent of dental caries.
    • Current vaccine development efforts are reviewed.

    Purpose of the Study:

    • To review the current knowledge on developing a safe and effective vaccine against dental caries.
    • To assess the progress and challenges in utilizing Streptococcus mutans for vaccine production.

    Main Methods:

    • Review of existing scientific literature on dental caries vaccines.
    • Analysis of research focusing on Streptococcus mutans as a target.
    • Evaluation of methods using whole cells versus purified components for immunization.

    Main Results:

    • Most research targets Streptococcus mutans, assuming its primary role in caries.
    • Early vaccine attempts used whole or broken bacterial cells.
    • Recent research explores purified cell components to enhance vaccine safety.

    Conclusions:

    • Producing a completely safe and effective dental caries vaccine remains a significant challenge.
    • Ensuring vaccine safety and efficacy, along with establishing long-lasting protection, are key hurdles.
    • Further research into purified immunogens and immunization schedules is necessary.

    Related Experiment Videos