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A flexible and versatile program for blood-gas quality control.

R C Elser, J Sitler, C Garver

    American Journal of Clinical Pathology
    |October 1, 1982
    PubMed
    Summary
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    A new quality control program uses tonometered whole blood for consistent blood gas analysis. This method links quality control data to maintenance, improving accuracy and instrument comparison.

    Area of Science:

    • Clinical Chemistry
    • Medical Diagnostics
    • Quality Control in Laboratories

    Background:

    • Accurate blood gas analysis is crucial for patient diagnosis and management.
    • Existing quality control methods may be influenced by environmental factors like barometric pressure.
    • Integrating quality control data with instrument maintenance is essential for reliable results.

    Purpose of the Study:

    • To develop and validate a novel quality control program for blood gas analysis.
    • To establish a quality control system independent of barometric pressure fluctuations.
    • To enable direct correlation between quality control data and instrument maintenance procedures.

    Main Methods:

    • Utilizing whole blood tonometered at multiple partial pressures of carbon dioxide (pCO2) and oxygen (pO2) as control material.

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  • Employing a precision gas mixer (Corning Model 192) and a two-channel syringe tonometer (Corning Model 184).
  • Implementing a recording format that consolidates results for direct comparison with maintenance actions and electrode performance.

    • Main Results:

    • The developed program provides control values independent of barometric pressure.
    • Levy-Jennings charts can be used with constant mean values for tonometered blood.
    • Electrode linearity is evaluated across a wide range of partial pressures, allowing for accurate assessment of proportional response and pO2 correction factors.

    Conclusions:

    • The tonometered blood quality control system offers advantages for assessing electrode performance and instrument differences.
    • This program enhances the reliability of blood gas analysis by linking quality control to maintenance.
    • The method allows for more accurate assignment of oxygen correction factors through recovery of theoretical values.