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Updated: Aug 25, 2026

Measuring Bacterial Load and Immune Responses in Mice Infected with Listeria monocytogenes
Published on: August 9, 2011
[Sensitivity of Listeria strains to drugs and disinfectants]
Abstract:
Comparative studies were carried out with 8 antibiotics, furazolidon, and 9 disinfection agents with regard to the sensitivity of a total of 14 strains of Listeria monocytogenes. The agents used were the most commonly employed ones in the practice in routinely applied concentrations. It was found that L. monocytogenes strains isolated from sheep had good sensitivity to the action of erythromycin, and penicillin, and were more slightly sensitive to chloramphenicol, gentamycin, tetracycline, and furazolidon. They were resistant to streptomycin and polymixin M. Good disinfection action against L. monocytogenes were shown to have formalin, phesiaform and partly phasiacept. Lower was the effect of sodium hydrate, proserine, and abosanite, while potassium permanganate, creolin, and chloramine did not show any bactericidal action.
Insights
Listeria monocytogenes strains from sheep showed sensitivity to erythromycin and penicillin. Formalin and phesiaform demonstrated effective disinfection against these Listeria monocytogenes strains.
Area of Science:
- Microbiology
- Veterinary Medicine
- Infectious Diseases
Context:
- Listeria monocytogenes is a significant pathogen in livestock, particularly sheep.
- Understanding antimicrobial and disinfectant efficacy is crucial for controlling outbreaks.
- Commonly used agents in veterinary practice were evaluated.
Purpose:
- To assess the sensitivity of ovine Listeria monocytogenes strains to various antibiotics and disinfectants.
- To identify effective treatments for Listeria monocytogenes infections in sheep.
- To compare the bactericidal and bacteriostatic properties of selected agents.
Summary:
- Fourteen Listeria monocytogenes strains isolated from sheep were tested against 8 antibiotics and 9 disinfectants.
- Erythromycin and penicillin showed high efficacy, while streptomycin and polymyxin M were ineffective.
- Formalin, phesiaform, and phasiacept exhibited good disinfection properties against Listeria monocytogenes.
Impact:
- Provides data for selecting appropriate antibiotics and disinfectants in veterinary settings.
- Informs strategies for preventing and treating Listeria monocytogenes infections in sheep.
- Contributes to the knowledge base on antimicrobial resistance and disinfectant effectiveness.
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