[Posttraumatic pituitary insufficiency. Value of pretreatment with LHRH in the differentiation between pituitary and...

A patient presented with post-traumatic hypopituitarism, where transient diabetes insipidus, high prolactin levels and prolonged and delayed TSH rise after TRH suggested a hypothalamic lesion. Although there was no gonadotropin response to LHRH as one could have expected, following repeated administration of LHRH, the LH response returned to normal, thus confirming a hypothalamic cause for his hypogonadism.