Transneuronal transport in the visual system of the toad, Bufo marinus

Secondary optic projections were studied in the toad, Bufo marinus using the method of transneuronal transport of triated proline and fucose. Following a survival of 14 days after eye injection autoradiographic label was transported transneuronally to the contralateral nucleus isthmi, the deeper layers of the contralateral tectum, the pontine region, the ipsilateral tectum and to the contralateral thalamus. Toads which survived 21 days or longer exhibited transneuronal transport of isotope to the contralateral telencephalon. The labelled patch in the telencephalon was located in the striatum, in the region of the lateral forebrain bundle.