[Effect of specific vaccinal antigens and preparations on general resistance in growing experimental and domestic...

Studied was the effect of some viral and bacterial antigens as well as of a preparation obtained by Filatov's method (modified by the author) on the general resistance in growing laboratory and domestic animals. It was found that in infantile albino mice the best protection against challenge with Escherichia coli and Pasteurella avicida was provided through the treatment with a biostimulator and a killed culture of a strongly proteolytic, unidentified strain of the 'T3' bacterium. The vaccines against Newcastle disease, hog cholera+erysipelas, and anthrax were shown to have a weaker action. It was also established that the treatment of fattening calves and sucking pigs with a biostimulator raised the general resistance of animals. This was demonstrated with the higher resistance to diseases caused by occasionally pathogenic organisms, the better general state, and the higher weight gain. Sucking pigs treated twice with a biostimulator at an interval of twelve days showed 13.27 per cent lower mortality rate as compared with the controls.