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Meningioma with pseudoglandular pattern. A case report.

J J Kepes, S Goldware, R Leoni

Journal of Neuropathology and Experimental Neurology

|January 1, 1983

Summary

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A rare falx meningioma mimicked adenocarcinoma due to its pseudoglandular pattern. Recognizing this variant is crucial to avoid misdiagnosis of metastatic tumors.

Area of Science:

Neuropathology
Surgical Pathology

Background:

Meningiomas are tumors arising from the meninges.
Histological variants of meningiomas can present diagnostic challenges.

Observation:

An 11-year-old girl presented with a falx meningioma exhibiting hemangiopericytomatous and papillary features.
The dominant histologic pattern was a pseudoglandular arrangement, mimicking adenocarcinoma.

Findings:

Gland-like spaces formed from dissolved cell nest centers and fused papillary processes.
The meningioma recurred locally five years post-surgery, retaining its pseudoglandular morphology.

Implications:

Awareness of the pseudoglandular meningioma variant is essential for accurate diagnosis.

Related Experiment Videos

Distinguishing this variant prevents misdiagnosis of metastatic adenocarcinoma and other mimics.