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Ascites causing a false-positive radionuclide liver image.

A G Williams, J H Christie, F A Mettler

    Clinical Nuclear Medicine
    |February 1, 1983
    PubMed
    Summary
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    False-positive liver scans can mimic lesions due to adjacent fluid. Ultrasonography confirmed ascites, not a liver abnormality, resolving the apparent "cold" lesion in the left lobe.

    Area of Science:

    • Radiology
    • Medical Imaging
    • Hepatology

    Background:

    • Radionuclide imaging of the liver can yield false-positive results.
    • These inaccuracies often stem from external factors impinging on the liver.
    • Adjacent masses, fluid collections, or normal anatomical structures can distort imaging.

    Observation:

    • A patient presented with an apparent "cold" lesion in the left lobe of the liver on radionuclide imaging.
    • This finding was associated with ascites in the anterior subphrenic space.
    • The apparent lesion was localized to the anterior subphrenic space.

    Findings:

    • Ultrasonography revealed a normal left lobe of the liver.
    • The ultrasound examination successfully localized the fluid collection to the anterior subphrenic space.

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  • The "cold" lesion on the radionuclide scan was determined to be a false positive caused by the adjacent ascites.

    • Implications:

    • Accurate interpretation of radionuclide liver imaging requires consideration of adjacent structures.
    • Ultrasonography is a valuable tool for differentiating true liver lesions from extrinsic artifacts.
    • This case highlights the importance of correlating imaging findings with clinical presentation and other diagnostic modalities.